Rapid enantiomeric separation of polychlorinated biphenyls by electrokinetic chromatography using mixtures of neutral and charged cyclodextrin derivatives.

Comparison of charged cyclodextrin derivatives for thechiral separationof atropisomericpolychlorinated biphenyls by capillary electrophoresis Charged cyclodextrin (CD) derivatives were used as chiral selectors in electrokinetic chromatography (EKC) for the chiral separation of highlyhydrophobic neutral racemates

Charged cyclodextrin (CD) derivatives were used as chiral selectors in electrokinetic chromatography (EKC) for the chiral separation of highlyhydrophobic neutral racemates such as atropisomeric polychlorinated biphenyls (PCBs). -CD-phosphated, -CD sulfated, succinylated-CD (Succ-CD) and succinylated-CD (Succ-CD) were used as anionic CDs. As cationic CD, 6-monodeoxy-6-monoamino-CD ( -CD-NH2) was...

Fast enantiomeric separation of uniconazole and diniconazole by electrokinetic chromatography using an anionic cyclodextrin: application to the determination of analyte-selector apparent binding constants for enantiomers.

The enantiomeric resolution of the fungicides uniconazole and diniconazole was performed using electrokinetic chromatography with cyclodextrins as pseudostationary phase (CD-EKC). A systematic evaluation of several chiral selectors was made. The anionic derivative carboxymethylated-gamma-cyclodextrin (CM-gamma-CD) was found to be the most appropriate for the enantioseparation of fungicides amon...

Method development of enantiomer separations by affinity capillary electrophoresis, cyclodextrin electrokinetic chromatography and capillary electrophoresis-mass spectrometry.

Capillary electrophoresis (CE) has become a powerful tool for enantiomer separations during the last decade. Since 1993, the author has investigated enantiomer separations by affinity capillary electrophoresis (affinity CE) with some proteins and by cyclodextrin electrokinetic chromatography (CDEKC) with some charged cyclodextrins (CDs). Many successful enantiomer separations are demonstrated f...

Enantiomeric separation of primaquine, an anti-malarial drug, by cyclodextrin-modified micellar electrokinetic capillary chromatography.

Separation of 1,4-benzodiazepine Derivates by Cyclodextrin Modified Micellar Electrokinetic Chromatography

The electrophoretic separation of electrically neutral benzodiazepines (BZDs) can be achieved by micellar electrokinetic chromatograpy (MEKC). The cyclodextrin (CD)-modified micellar electrokinetic chromatography separation of eight of the most frequently used BZD was obtained within 15 minutes at + 25 kV on a 64.5 cm x 50 μm I.D. silica capillary at 25C, using a 25 mM sodium tetraborate-50 mM ...